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Rural older women offer insight for why nature is important when aging in place

In a new study, Penn State College of Nursing Project Director Erica Husser—a developmental gerontologist with a passion for nature and older women’s health—investigated the perceived influence of nature on the daily lives of rural older women living with multiple chronic health conditions.

According to Husser, we are hard-wired to pay attention to nature early in life, but as we develop, the ways in which people come to understand, value, and experience nature will vary. Considering how dramatically many lives have shifted and how uncertain the days continue to be in response to the coronavirus pandemic, Husser said the perceptions and experiences that rural older women have with nature can offer insights that may help others cope with, and adapt to changes that are out of our control.

Husser said that culture, demographic characteristics, family norms and behaviors, and personal experiences all shape who we are and how we experience nature with differential impacts, but the science is clear: nature can nurture. Research examining the influence of nature on behavioral and psychosocial characteristics has showed positive outcomes for factors like heart rate, blood pressure, attention, cognitive function, social interaction, neighborhood satisfaction, and quality of life.

“Traditionally, older women have had fewer seats at the table and their voices marginalized,” Husser said. “They seem to disappear from society and not many people pay attention to them. Institutionally, academia has mostly overlooked older women, so we don’t have much research on their views about the natural environment, and they have a set of values I think we could all learn from.”

Rural older women and the importance of nature

Research conducted through Penn State College of Nursing investigated the perceived influence of nature on the daily lives of rural older women living with multiple chronic health conditions.

Understanding those values and the potential impact nature could have on older women’s health and well-being, Husser sought to learn how rural older women related to their natural surroundings. She conducted in-depth face-to-face interviews with 34 women aged 71 to 91, living in rural southwest Virginia. What she discovered were intimate and important connections between nature and the women’s perceived well-being and quality of life, as they were experiencing aging in place.

“The women identified with nature, and they were immersed in it, daily,” Husser said. “They felt like it was part of who they were, and it provided them joy, helped them relax, engaged their mental and emotional processing, and for some, it strengthened their sense of community.”

Further elaborating on how the women identified with nature, Husser found that the women perceived nature to be the environment “right outside their door.” Most women described a spiritual connection with nature, viewing it as God’s creation. The study found that interacting with nature activated their faith in God, helping them reconcile and cope with health challenges, personal trauma, or natural disasters.

“At some point, people become less interested with materialistic and rationalistic ways of being and they transition toward a more cosmic perspective that involves less concern for self, and increased interest in reflecting, exploring, and engaging more cognitive energy toward intangible and often-times existential questions and ideas,” Husser said. “Nature seems to be one of the spaces that really allows for reflection, and potential growth and existential understanding to be experienced.”

Husser said that while nature served as a spiritual connector for a majority of the women, several others also described their experiences as emotionally and intellectually stimulating, which motivated continued engagement. They felt nature provided them with relaxation, energization, liberation, and an opportunity to learn more about nature, all of which contributed to enhanced cognitive engagement—an essential component of mental and emotional health.

As people struggle to cope with the developing coronavirus pandemic and its effects on their daily lives, Husser said these older women provide the perspective that time spent in nature can serve as an avenue for managing and adapting to feelings of loss, grief, isolation and confinement. Fear of contracting the virus, government mandated lockdowns, stay-at-home orders, and the transition to telecommunication emphasize the need to practice good self-care to help manage anxiety, stress, and concerns about liberty and independence. For these aging women, spending time in the natural environment enhanced their sense of freedom and provided a buffer against feelings of confinement.

“You just see things like rabbits and turkeys; the field will be full of turkeys,” said one 75-year-old woman. “I just like it, and it makes you feel like you are not closed in.”

These themes of enjoying nature, spiritual connections through nature, and emotional and intellectual health and well-being with respect to being immersed in nature do not translate across all groups, according to Husser, who added it’s important to understand that as we age, we become more diverse, and that diversification paves the way towards more meaningful research.

“We have to steer this popular fear of aging away from a horrible doom-and-gloom type of scenario toward something more realistic,” Husser said. “Aging can be about the beauty of your lifelong learning and the integration of your experiences coming to fruition to support yourself as your physical health, and the world around both change. Knowing what you need to feed your own spirit and to energize yourself is important.”

As research continues to untangle the relationship between the natural environment and improved mental, emotional, and cognitive health, individuals experiencing a loss of control or feelings of isolation due to the coronavirus pandemic may find comfort and support in learning about the life experiences and perspectives of these older women aging in rural America.

Husser directs Age Friendly Care, PA, a collaboration between the College of Nursing, CGNE, the College of Medicine, the Primary Health Network (PHN), Area Agencies on Aging, and the Alzheimer’s Association, and the Pennsylvania Department of Aging. The program aims to educate and implement the 4Ms of Age Friendly Care—what Matters, Medication, Mentation and Mobility—across health systems, community groups, families, and individuals throughout the commonwealth over the next five years.

Putting her research into the context of the 4Ms of Age-Friendly Care, Husser explains that spending time in nature informs what matters to these women. Knowing what matters empowers health care providers to individualize and align care that harnesses and supports the values of each patient. What matters anchors and informs the other care decision related to mobility, medications, and mentation.

“My colleagues in the College of Nursing and my supervisor provided me with flexibility, support, and the encouragement I needed to get this work published,” Husser said. “I can’t say enough about the power of mentorship and peer support; it has allowed this research to emerge.”

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Cold War antiseptic has potential in fight against drug-resistant germs and viruses

A little-known non-toxic antiseptic developed in the Soviet Union during the Cold War has enormous potential to beat common infections, say University of Manchester scientists.

Miramistin, developed for the Soviet Space Program and little known in the West, can inhibit or kill influenza A, human papilloma viruses that cause warts, coronaviruses, adenoviruses, and human immunodeficiency virus (HIV).

The potion is much less toxic to human cells than conventional antiseptics such as cyclohexamide and cetylpyridinium chloride, and is also biodegradable.

It can be used against Candida and Aspergillus species, and also kills bacteria, including Stарhуlососсus, Proteus and Klebsiella as well as the bugs that cause syphilis and gonorrhea.

Miramistin is still used in some of the former countries of the Soviet Bloc in hospitals and surgeries, mainly to treat to treat wounds and ulcers.

However, it is barely known elsewhere and there is almost no mention of it in the English literature.

“Conventional antiseptics contaminate the environment because they are toxic to microbiota, fish, algae, and plants,” said Professor David Denning from the University of Manchester, who was on the research team. “These are widely available but problematic, whereas Miramistin has no genotoxic effects after it has been broken down.”

Dr. Ali Osmanov says, “Miramistin has been overlooked in the West and may have practical and environmental advantages.”

Widely used antiseptics with chlorinated aromatic structures including triclosan and triclocarban barely degrade and so persist in the environment for long significant periods, even decades. In contrast, Miramistin is 88–93% biodegradable

The study is published in the journal FEMS Microbiology Reviews.

Lead author Dr. Ali Osmanov, awarded a scholarship to study fungal disease at Manchester, examined Miramistin in the lab for his dissertation project.

When in his native country, Ukraine, he discovered extensive clinical use of Miramistin, causing him to consider if it might be useful elsewhere.

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Popular chemotherapy drug may be less effective in overweight and obese women

Breast cancer patients who are overweight or obese might benefit less from treatment with docetaxel, a common chemotherapy drug, than lean patients. An international team of researchers based this conclusion on a retrospective analysis of data from a large clinical trial. Their study was published in the Journal of Clinical Oncology.

In most European countries, more than 50% of women are overweight or obese (with a body mass index (BMI) above 25 kg/m2, as defined by the WHO). In the United States this is the case for over 63% of women and this proportion is expected to further increase in the coming years. It is not widely known, but obese women have a higher risk of getting breast cancer and obese breast cancer patients have a higher risk of relapsing. Moreover, while many cancer patients are overweight or obese, the efficacy of anticancer drugs according to their BMI is generally not known.

Analysis of 2,800 patients

For the study, a team led by researchers from KU Leuven and the Institut Jules Bordet (Belgium), the University of Milan and National Cancer Institute (Italy) analyzed data from a clinical trial with over 2800 breast cancer patients that started around the turn of the millennium. Patient data were collected over the course of more than ten years. The patients in the trial were treated with a combination of chemotherapy drugs with or without docetaxel, one of the most widely used chemotherapy drugs in the world.

The researchers then looked at how many patients relapsed and how many had passed away. Their statistical analysis of the data shows that overweight and obese patients who received docetaxel as part of their treatment had poorer outcomes than lean patients (BMI between 18.5 and 25 kg/m2). This difference was not observed in patients who received the chemotherapy regimen that did not include docetaxel. “Docetaxel is a lipophilic drug, suggesting that fat present in the body could absorb part of the drug before it can reach the tumor,” explains Professor Christine Desmedt from the KU Leuven Laboratory for Translational Breast Cancer Research.

Raising public awareness

The results raise concerns about treating overweight and obese cancer patients with docetaxel.

“If follow-up research confirms that this finding is solely related to the pharmacological characteristics of docetaxel, this might also apply to patients with other cancer types that are treated with docetaxel, such as prostate or lung cancer. These results also make us wonder whether other chemotherapy drugs from the same family, like paclitaxel, will show the same effect. More research is needed before changes in treatment can be implemented. Patients who have concerns about docetaxel can discuss these with their doctor,” explains Professor Desmedt.

“In general, the public needs to be better informed about the link between BMI and breast cancer.”

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US marks record 53,069 coronavirus cases in 24 hours: tracker

Credit: CC0 Public Domain

The US notched more than 53,000 new COVID-19 cases in 24 hours Thursday, a tally by Johns Hopkins University showed, a new one-day record as infections surge around the country.

The Baltimore-based university’s tracker showed 53,069 more cases as of 8:30 pm (0030 Friday GMT), bringing the total number of cases since the pandemic reached the United States to 2,735,339.

The university also recorded a further 649 fatalities, bringing the total death toll to 128,677.

The second consecutive day of a record-high case count came as the United States—the hardest-hit country in the world in the coronavirus pandemic—headed into the long July Fourth holiday weekend.

Florida is a key focus of public health experts worried about a surge in southern and western US states and it now has more than 169,000 cases.

Governor Ron DeSantis blamed the rise on “social interactions” among young people gathering at parties, beaches, bars, swimming pools and elsewhere, as well as a more “robust” testing program.

In Texas, where more than 2,500 people have died, Governor Greg Abbott ordered people in counties with 20 or more cases to wear masks, and banned gatherings of more than 10 people.

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A novel sperm selection technology to increase success rates of in vitro fertilization

Motile sperm are difficult to collect with a conventional cell sorter because they are vulnerable to physical damage. A research collaboration between Kumamoto and Kyoto Universities in Japan has developed a technique that uses a cell sorter with microfluidic chip technology to reduce cell damage and improve in vitro fertilization (IVF) rates. This research is expected to increase IVF rates to improve production of experimental animals and livestock, and could be used as a fertility treatment in human reproductive medicine.

It is important to select fertile sperm with good motility to obtain high IVF rates. Conventional cell sorters use flow cytometry to separate specific cells by type, and can be used to select sperm. However, since sperm cells are susceptible to physical damage, it is extremely difficult to separate them without effecting motility.

To reduce sperm cell damage, Professor Toru Takeo’s research team at Kumamoto University tried to develop a sperm selection technique using a cell sorter with microfluidic chip technology that reduces detrimental effects to cells. Microfluidic devices have minute channel structures with a width and depth between several to several hundreds of micrometers and are widely used in chemical and biotechnology research.

While investigating the optimum separation conditions of sperm from a culture medium with their device, the researchers successfully collected mouse sperm that maintained motility. Furthermore, IVF using sperm collected with this device produced fertilized eggs and the embryos developed into neonatal mice after being transplanted into female mice.

This new technology can also be used to improve IVF. At the end stage of maturation, before egg penetration and fertilization, sperm undergo morphological and physiological changes called the acrosome reaction that makes them ready to fertilize an egg. To test whether they could increase fertility, researchers prepared a fluorescent substance that binds to fertile sperm and used the device to sort them from non-fertile sperm. Comparison IVF experiments revealed that the fertile sperm had a higher fertilization rate than the non-fertile sperm.

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Joanna Gaines Stopped Micromanaging in Order to Spend More Time With Kids

The key to motherhood! Joanna Gaines stopped relying on micromanaging to balance her career with her five children.

Chip and Joanna Gaines’ Best Quotes About Family and Parenthood

“This business isn’t going to run me, I’ve got to run this business,” the Fixer Upper alum, 42, said on Wednesday, July 1, during Salesforce Presents Stories of Resilience: A Conversation With Chip and Joanna Gaines on Finding Inspiration. “I’m busier, I have more on my plate, but I dictate what I’m doing and what the business is going to do for me. When you get that kind of passion and mindset, you start saying yes to what you need to say yes to and let others do what [you] used to control and micromanage. I’m going to let the team do it because they’re going to crush it.”

When the Kansas native isn’t working, she “carves out intentional moments” to refill her tank, explaining, “I have space in the home to create and to cook and do all the things that bring me life, then when I go to work, I feel full and energized.”

Full House! Mel Gibson and More Celeb Parents With Big Broods

The former reality star, who shares Drake, 15, Ella, 13, Duke, 12, Emmie, 10, and Crew, 2, with Chip, 45, acknowledged that she is “more of a robot than a human.” Joanna said, “Now I’m so in tune with my mind and my emotional state that [I realize], ‘Oh, I’m running low. I need to pull back. I need to get in the garden, I need to get with the kids.’”

This practice helps the Magnolia Table author from “feeling depleted,” she said, and her husband encouraged other working parents to follow her example.

“She can actually do more with less if she gives herself, her body, her mind, her spirit, all the things that make us human,” the Capital Gaines author chimed in. “She has much more to give the house, family [and] business.”

The couple tied the knot in 2003 and started growing their family two years later. Chip will still “want more kids” when Joanna is 50, she joked to Willie Geist in October 2019.

Joanna and Chip Gaines’ Family Album

“Chip with children is like business — there’s never too many,” the former reality star explained at the time. “I’m like, ‘Chip I think we’ve got enough, I think we’re good!’ That’s how Chip is with children. He’s like, ‘I just think we can keep having them!’ I think Chip just loves a full plate.”

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Apgar score effective in assessing health of preterm infants

The vitality of preterm infants should be assessed with an Apgar score, a tool used to measure the health of newborns immediately after birth. That is the conclusion by researchers at Karolinska Institutet in Sweden who in a large observational study examined the value of Apgar scores for preterm infants. The findings are published in the New England Journal of Medicine.

The so-called Apgar score has been used since the 1950s to quickly assess the vitality of the infant soon after birth. Doctors and midwifes measure five parameters in the infant—heart activity, respiration, muscle tone, irritability and color—and give each parameter a score from 0-2. The total score can thus range from zero to 10, where a higher number indicates better health and a greater chance of survival.

However, some have questioned the value of the Apgar score in preterm infants, since the immaturity of these infants may lead to lower scores compared with infants born at term. Therefore, the researchers in this study wanted to find out if the Apgar score could be used to predict the mortality risk of preterm infants during the first four weeks of life (the neonatal period).

Using Swedish nationwide register data, the researchers studied 113,000 non-malformed infants born after 22 to 36 weeks of pregnancy in the years 1992-2016. The risk of neonatal mortality was calculated for Apgar scores at five and ten minutes after birth, and separate analyses were performed for infants born at 22-24, 25-27, 28-31, 32-34 and 35-36 gestational weeks.

Lower Apgar score increased risk of neonatal death

A total of 1,986 (1.8 percent) preterm infants died in the neonatal period. As expected, the neonatal death rate sharply increased with shorter pregnancy length, from 0.2 percent for infants born at 36 weeks to 76.5 percent for those born at 22 weeks. Regardless of pregnancy length, the risk of neonatal death increased with a lower Apgar score. For children born very prematurely, a lower Apgar score significantly increased the absolute risk of neonatal mortality. Even a slight increase in Apgar score from five to ten minutes after birth was associated with a lower risk of neonatal death.

“Our results show the importance of registering Apgar score also in preterm infants,” says Sven Cnattingius, senior professor at the Department of Medicine, Solna, Karolinska Institutet, and the study’s corresponding author. “It is important that infants with reduced scores receive full clinical attention regardless of gestational age.”

Co-author Stefan Johansson, associate professor at the Department of Medicine, Solna, Karolinska Institutet and neonatologist at the Sachsska children and youth hospital in Stockholm, says, “Heart activity and breathing are the cornerstones of the Apgar assessment. Our research indicates that the chance of survival increases the better you are at stabilizing the premature baby’s circulation and breathing immediately after birth.”

The researchers considered several confounding factors that could impact the outcome, including the mother’s age, smoking, weight, blood-pressure, infant’s mode of delivery and year of birth. The researchers note that the study is based on Swedish conditions and that the results may be different in other countries.

Best available tool

“Although it is frustrating that we usually cannot pinpoint the causes of a reduced Apgar score, we need to embrace that the score is, independent of gestational age, the best available tool we have to evaluate the newborn’s health in the delivery room,” says Neda Razaz, assistant professor in the same department.

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16-year-old reveals the heartbreak of having a premature baby in lockdown

When teenager Kimmy Simper welcomed her first child Lucas on 11 February, her tiny baby was just one week and two days past the point of the pregnancy being considered ‘viable’.

Weighing just 2lbs 2oz, Kimmy’s son had to rely on breathing equipment to help him survive as he spent the next four months in a Neonatal Intensive Care Unit. If that wasn’t enough, the little boy has already spent most of his life living in lockdown.

Today Lucas is doing well – but it’s been a tough ride and a devastating time for Kimmy and her family.

At just 16, her pregnancy was unplanned. Kimmy wasn’t in a relationship with the baby’s father and admits she felt thankful for her family’s support after breaking the news to them.

Even so, when she went into early labour, the teenager couldn’t help but feel terrified.

After three days of experiencing stomach pain, Kimmy had decided to get checked out at the hospital.

Initially she was told she was just experiencing braxton hicks, normal contractions of the uterus that can happen during pregnancy.

But the next day, Kimmy couldn’t feel her baby boy moving.

She tells Metro.co.uk: ‘They checked his heartbeat and said that everything was fine, so went to send me home.

‘The pains got worse, so I went to the toilet in the hospital and saw fresh blood and what was my mucus plug. I told the midwife that had just seen me, and she popped me into the bed to see that I was actually fully dilated.’

Knowing they had to act fast as Kimmy was still so early on in her pregnancy, the midwife hooked Kimmy up to a steroid drip in a bid to help mature Lucas’ frail lungs and began his delivery.

‘Within 30 minutes he was out,’ she remembers.

‘I was so petrified because I knew this wasn’t normal and I had no idea what the outcome would be.’

Kimmy says giving birth at just 25 weeks pregnant was incredibly upsetting and scary, as she knew there was a chance her son wouldn’t make it.

‘I was really overwhelmed and didn’t know what to feel,’ she says. ‘They took him straight away, and I didn’t see him for seven hours after the birth.’

Things became even harder when Boris Johnson announced lockdown to slow the spread of coronavirus on 23 March, while Lucas was still in hospital.

Luckily, Kimmy was still able to visit Lucas during the day – but she had to go home without him each night.

She explained: ‘I came at 9am and went at 8pm. The hardest part was going home without him.

‘The lockdown makes this so much harder as the restrictions mean only the mums could visit. This meant that I had to put up with all of the bad days as well as the good on my own.

‘It’s very emotionally draining, and I’m lucky I have support in the hospital as well as at home because of my mental health problems.

‘My family are trying the best they can to support me but they said that they will never understand how I feel because they haven’t been through what I have.’

As restrictions were put into place in hospitals, the new mum had to wear a mask, gloves and an apron to visit her son.

It also meant Lucas wasn’t allowed out for any cuddles and she was rarely allowed to touch him. Kimmy says even the nurses found this difficult, as before lockdown they would encourage physical contact as often as possible.

Kimmy continues: ‘The hygiene at the hospital was always the same because of the environment that we were in, however the tension and the new rules brought in due to Covid-19 made it a lot harder to enjoy spending time with my baby.

‘It’s made my emotions sky high and I’ve found it much more difficult to stay positive, however I’ve tried my hardest for my baby boy.’

Since his birth, Lucas has experienced many health problems. At week one, his bowel split and he needed an emergency operation to have a stoma (an opening on the front of your abdomen to allow faeces or urine to be collected in a pouch) created, and at two weeks he required a heart operation for his PDA ligation (when oxygen-rich blood that should circulate around the body returns to the lungs).

He then had another operation to have his stoma closed at two-and-a-half months old, and then had an operation on his eyes for retinopathy of prematurity (ROP), which left untreated can result in blindness.

Kimmy says: ‘He’s recovered very well from all his surgeries. He’s got problems with his blood pressure, kidneys and liver, so will be having regular check ups for that. We will also come back to hospital every week for his eyes too.’

On 2 June, Lucas was able to leave the hospital for the first time since he was born 16 weeks before.

Kimmy says the challenges she and Lucas faced have made her feel even luckier to finally have her son at home.

She says: ‘It’s made me appreciate every little thing so much more. I’ve had to fight for my baby, and it’s made me so much stronger.

‘Each day is a new day, one step at a time.

‘I’m so, so, so happy and excited to finally take my baby boy home.

‘I’ll be able to get into my own routine and finally do things the way I want. I’m scared because of lockdown, but it just means I can spend more time with him.

‘Only my household will be holding him as I need to shield him because he’s coming home on oxygen.’

As advice for any other new mums going through a similar time during lockdown, Kimmy says: ‘Each day will be a challenge, and you’ll feel like you’re never making any progress, but these babies are much stronger than you think.

‘You just being there to hold their hand will give them the strength you need. Even if you can’t be there for them because of lockdown, there’s little things you can do, and they won’t remember or hold it against you.

‘You stay strong for them, they will stay strong for you.

‘Everything is worth it in the end.’

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Personal Health

Morning sickness in pregnancy, not only in the morning

Nausea and vomiting in pregnancy are often under the term "Morgenübelkeit" summarized. Researchers at the University of Warwick suggest, however, that these symptoms can occur in many any time of the day.

Under "Morgenübelkeit" refers to Nausea and vomiting, which occur in the first weeks of pregnancy often. So far, however, no research work have been busy, to occur what times of the Day, these symptoms actually. British scientists have caught up now, and found that vomiting occurred mainly between 7 and 13 PM, and Nausea throughout the whole day. Some women also suffered to in the evening vomiting. Between 9 and 10 o’clock, 82 percent of respondents Nausea and 29 percent felt had vomiting. 94.2 percent of the women had a 58% both symptoms.

Came Nausea especially in weeks 5, 6 and 7 of the pregnancy, while vomiting was observed in week 7. Since the study ended after seven weeks of pregnancy, can be said for the later phases nothing about the frequency of these symptoms out.

Ünausea and vomiting: Häsingle-stage basic für hospital admissions

Professor Roger Gadsby, of Warwick Medical School said: "If a pregnant woman vomits in the afternoon, you may feel that this is unusual. If she has no vomiting, but all day Nausea is suffering, could you think that you are not under ‚Morgenübelkeit‘ suffers. Those women who suffer from severe symptoms, get the feeling that your condition trivia is updated." Severe Nausea and vomiting can have a significant impact on the quality of life of pregnant women and in the first trimester of pregnancy, the most common cause for admission to hospital.

ZOU

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Vaccine Team reports success: In a few weeks, a decisive Phase will begin

A worldwide hunt is a vaccine against the new Coronavirus. With the race Biontech from Mainz, Germany, and the US group Pfizer is. You speak of encouraging results after Tests in the United States. Still, however, must be followed by further larger studies.

On the search for a vaccine against the new Coronavirus, the Mainz-based Biopharma company Biontech and the US company Pfizer have come at least a certain step forward. In Tests in the USA have developed subjects effective antibodies against the causative agent of Sars-CoV-2. The Biontech and Pfizer announced on Wednesday, together. It is unclear whether these antibodies actually protect against infection with Sars-CoV-2. The are now to show Tests with up to 30 000 volunteers.

Positive mood at experts

Several experts rated the results positively. The immunologist Bernhard Fleischer, former Director of the Bernhard-Nocht-Institute for tropical medicine, said the results were “quite remarkable”. He would assume to be the vaccine against an infection with the Coronavirus protected. It had not been proved but still.

  • Read also: All the News in the Live-Ticker to the Corona-crisis

The already performed Tests in the United States consisted of 45 healthy volunteers aged 18 to 55 years of age. 24 of them received two injections of the drug – some in a slightly higher dose. Twelve subjects received at least once in a high dose, this approach was not pursued further. Added to this was a nine-person control group, which received two doses of Placebo. If two doses were administered, this was done at intervals of three weeks. dpa/Andreas Arnold/dpabild company building of the company Biontech to see. Prior to that, a truck drives past.

Subjects with antibody against Coronavirus form

Seven days after the second vaccination were noted in all 24 subjects with two doses of antibody, which could turn off the Virus Sars-CoV-2 in a subsequent laboratory test. These people also showed a significantly stronger antibody formation than people who were already infected with Sars-COV-2. Depending on the vaccine dose, the Vaccinated 1.8 or the 2.8 had formed Times more neutralizing antibodies against the Coronavirus.

Serious side effects it came to the details of Biontech and Pfizer, according to the candidates with the two doses were observed only been “mild-to-moderate local and systemic reactions section. The most common local reaction was a pain at the injection site.

Whether the vaccine actually helps, is not yet proven

“These are quite good signals,” says Stephan Becker, a virologist at the University of Marburg. In particular, it was good that the anti-body concentration was higher than in the case of people who have made an infection. If the vaccine candidate is actually protecting against an infection, not shown by the results, but said Becker. dpa/Friso Gentsch/dpa/picture Icon , A syringe in front of a word “vaccination” to be held.

In addition, it is unclear whether vaccination for the construction of a so-called immune memory, so that the body is prepared to infection with the Coronavirus effective. To show this, you must be vaccinated many Thousands of people, to look to see how many of them are infected under real conditions with the Coronavirus. Becker is not involved in the Corona-projects of Biontech, but in co-operation with the company on other projects.

“An important and encouraging step”

“Data on the immune response to vaccination in humans are actually an important and encouraging step on the way to a vaccine,” said the President of the Paul-Ehrlich-Institut, Klaus Cichutek. This applies, in particular, in the case of an RNA vaccine as this, because there is no such authorised Human vaccines, and there is also little experience with “preventive RNA vaccines is in the world” there. In front of Biontech and Pfizer, the Biotech had been one of the company Moderna from the USA, the induction of an immune response in humans by an RNA vaccine candidates. It had been so, the world’s second note. Reuters/Stefan Albrecht/Biontech/dpa employees of the biotechnology company Biontech advice in the laboratory.

Biontech co-founder and chief Ugur Sahin called the preliminary data is very encouraging. They showed that the vaccine candidate “is capable of inducing an immune response with neutralizing antibodies in humans”. “We look forward to publishing additional data and BNT 162b1,” he said. Biontech is testing potential vaccines in Germany. It was in this country as the first company in the approval of the Paul-Ehrlich-Institute. BNT 162b1 is the Name of the vaccine candidate to the the US results. Kathrin U. Jansen, a Senior Vice President at Pfizer and for vaccine research, said the first clinical data agreed to be confident.

Right dose should be found – in a decisive Phase at the end of July

With the already made and subsequent Tests Biontech and Pfizer want to find out the correct dose for a possible vaccine. There is also a selection must be made, and with which vaccine candidates in a large-scale, global study with more than 30 000 healthy volunteers is being worked on. The could begin – unless it is approved by the authorities – in late July 2020. Reuters/Justin Lane/EPA The Pfizer Headquarters in New York.

Still BNT 162b1 be allowed in any country of the world for the use, stressed Biontech and Pfizer. “Should extend the study successfully, and the vaccine will receive regulatory approval, plan to the two companies until the end of 2020, up to 100 million doses of the Vaccine and to be able to until the end of 2021 may be more than 1.2 billion doses of the Vaccine to produce” more, more, and both companies in a joint press release. Would you make the vaccine all over the world available, except in China. There Biontechn collaborates with the Chinese group Fosun Pharma.

 

Here you will find the currently reported Figures by the health ministries of the countries.

  • Baden-Württemberg: 35.755 (1.838 Deaths)
  • Bavaria: 48.454 (2.591 Deaths)
  • Berlin: 8.301 (214 Deaths)
  • Brandenburg: 3.459 (171 Deaths)
  • Bremen: 1.673 (53 Deaths)
  • Hamburg: 5.206 (231 Deaths)
  • Hesse: 10.811 (507 Deaths)
  • Mecklenburg-Vorpommern: 803 (20 Deaths)
  • Lower Saxony: 13.548 (632 Deaths)
  • North Rhine-Westphalia: 43.241 (1.683 Deaths)
  • Rhineland-Palatinate: 7.027 (235 Deaths)
  • Saarland: 2.768 (173 Deaths)
  • Saxony: 5.450 (222 Deaths)
  • Saxony-Anhalt: 1.878 (59 Deaths)
  • Schleswig-Holstein: 3.163 (152 Deaths)
  • Thuringia: 3.258 (181 Deaths)

Total (As Of 01.07.20, 19.10 PM): 194.795 (8.962 Deaths)

The Day Before (As 30.06.20, 20.06 PM): 194.335 (8.957 Deaths)

Source to be Infected – and death-figures: country health and social ministries.

The number of Healed, according to the Robert Koch Institute in Germany, at around 179.800.

Currently, the RKI reported reproduction number: 0,86 (as of 01.07.20)

Surf tip: Coronavirus reproductive number and the smoothed R-value explained

“The best-informed Person on the Planet Erde": White house mired in contradiction