Novel bone imaging approach provides insights into the progression of knee osteoarthritis

A new approach to functional bone imaging has established that bone metabolism is abnormally elevated in patients with knee osteoarthritis. This physiological information provides a new functional measure to help assess degeneration of the knee joint. The research was presented at the Society of Nuclear Medicine and Molecular Imaging 2020 Virtual Annual Meeting, July 11-14. Osteoarthritis, the most common joint […]

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Researchers develop new approach to study the genetics of human disease

Many heritable immune diseases such as rheumatoid arthritis and blood-cell related traits derive from critical proteins not being made or not functioning correctly. But exactly how a person’s genes, the regulation of these genes and how the resulting proteins interact to cause disease is not widely understood. In a new paper published in Nature Genetics, University of Chicago researchers discovered […]

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Designing anew: Radical COVID-19 drug development approach shows promise

Nearly every drug that is, or has ever been, used was derived from nature—harnessing compounds created by organisms over eons to fight diseases. But decades ago, biochemists postulated that it might be possible to design a new drug from scratch by linking up amino acids in precise ways. The tricky part, as it turned out, was predicting in advance how […]

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A focused approach to imaging neural activity in the brain

When neurons fire an electrical impulse, they also experience a surge of calcium ions. By measuring those surges, researchers can indirectly monitor neuron activity, helping them to study the role of individual neurons in many different brain functions. One drawback to this technique is the crosstalk generated by the axons and dendrites that extend from neighboring neurons, which makes it […]

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